Molecular Profile Study of Extracellular Vesicles for the Identification of Useful Small “Hit” in Cancer Diagnosis

Tumor-secreted extracellular vesicles (EVs) are the main mediators of cell-cell communication, permitting cells to exchange proteins, lipids, and metabolites in varying physiological pathological conditions. They contain signature tumor-derived molecules that reflect intracellular status their cell origin. Recent studies have shown tumor cell-derived EVs can aid cancer metastasis through modulation microenvironment, suppression immune system, pre-metastatic niche formation, subsequent metastasis. easily be isolated from a variety biological fluids, content makes them useful biomarkers for diagnosis, prognosis, monitorization progression, response treatment. This review aims explore obtained liquid biopsies, order understand progression metastatic evolution early diagnosis precision therapy.